Evaluating outlier loci and their effect on the identification of pedigree errors

Homozygosity outlier loci, which show patterns of variation that are extremely divergent from the rest of the genome, can be evaluated by comparison of the homozygosity under Hardy-Weinberg proportions (the sum of the squares of allele frequencies) with the expected homozygosity under neutrality. Su...

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Bibliographic Details
Main Authors: Wang, Ke-Sheng, Liu, Michelle, Paterson, Andrew D
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866779/