Optimizing the evidence for linkage by permuting marker order

We developed a new marker-reordering algorithm to find the best order of fine-mapping markers for multipoint linkage analysis. The algorithm searches for the best order of fine-mapping markers such that the sum of the squared differences in identity-by-descent distribution between neighboring marker...

Full description

Bibliographic Details
Main Authors: Jun, Gyungah, Song, Yeunjoo, Iyengar, Sudha K, Elston, Robert C
Format: Online
Language:English
Published: BioMed Central 2005
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866721/