Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium
Current genome-wide linkage-mapping single-nucleotide polymorphism (SNP) panels with densities of 0.3 cM are likely to have increased intermarker linkage disequilibrium (LD) compared to 5-cM microsatellite panels. The resulting difference in haplotype frequencies versus that predicted may affect mul...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2005
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866698/ |