Drosophila SETDB1 Is Required for Chromosome 4 Silencing

Histone H3 lysine 9 (H3K9) methylation is associated with gene repression and heterochromatin formation. In Drosophila, SU(VAR)3–9 is responsible for H3K9 methylation mainly at pericentric heterochromatin. However, the histone methyltransferases responsible for H3K9 methylation at euchromatic sites,...

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Bibliographic Details
Main Authors: Seum, Carole, Reo, Emanuela, Peng, Hongzhuang, Rauscher, Frank J, Spierer, Pierre, Bontron, Séverine
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866353/