Immunity against Ixodes scapularis Salivary Proteins Expressed within 24 Hours of Attachment Thwarts Tick Feeding and Impairs Borrelia Transmission

In North America, the black-legged tick, Ixodes scapularis, an obligate haematophagus arthropod, is a vector of several human pathogens including Borrelia burgdorferi, the Lyme disease agent. In this report, we show that the tick salivary gland transcriptome and proteome is dynamic and changes durin...

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Bibliographic Details
Main Authors: Narasimhan, Sukanya, DePonte, Kathleen, Marcantonio, Nancy, Liang, Xianping, Royce, Thomas E., Nelson, Kenneth F., Booth, Carmen J., Koski, Benjamin, Anderson, John F., Kantor, Fred, Fikrig, Erol
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866177/