Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk

Both selective cyclooxygenase (COX)-2 inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs) have been beneficial pharmacological agents for many patients suffering from arthritis pain and inflammation. However, selective COX-2 inhibitors and traditional NSAIDs are both associated with height...

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Bibliographic Details
Main Authors: Chan, Edwin SL, Zhang, Hongwei, Fernandez, Patricia, Edelman, Sari D, Pillinger, Michael H, Ragolia, Louis, Palaia, Thomas, Carsons, Steven, Reiss, Allison B
Format: Online
Language:English
Published: BioMed Central 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860062/