A Mammal-Specific Doublesex Homolog Associates with Male Sex Chromatin and Is Required for Male Meiosis

Gametogenesis is a sexually dimorphic process requiring profound differences in germ cell differentiation between the sexes. In mammals, the presence of heteromorphic sex chromosomes in males creates additional sex-specific challenges, including incomplete X and Y pairing during meiotic prophase. Th...

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Bibliographic Details
Main Authors: Kim, Shinseog, Namekawa, Satoshi H, Niswander, Lisa M, Ward, Jeremy O, Lee, Jeannie T, Bardwell, Vivian J, Zarkower, David
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853120/