DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies

Transcription factor (TF) proteins recognize a small number of DNA sequences with high specificity and control the expression of neighbouring genes. The evolution of TF binding preference has been the subject of a number of recent studies, in which generalized binding profiles have been introduced a...

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Bibliographic Details
Main Authors: Mahony, Shaun, Auron, Philip E, Benos, Panayiotis V
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1848003/