HIV-1 Buds Predominantly at the Plasma Membrane of Primary Human Macrophages

HIV-1 assembly and release are believed to occur at the plasma membrane in most host cells with the exception of primary macrophages, for which exclusive budding at late endosomes has been reported. Here, we applied a novel ultrastructural approach to assess HIV-1 budding in primary macrophages in a...

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Bibliographic Details
Main Authors: Welsch, Sonja, Keppler, Oliver T, Habermann, Anja, Allespach, Ina, Krijnse-Locker, Jacomine, Kräusslich, Hans-Georg
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829407/