Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum

Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite genome underlies immune evasion. We compared the diversity of the DBLα domain of var genes sampled from...

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Bibliographic Details
Main Authors: Barry, Alyssa E, Leliwa-Sytek, Aleksandra, Tavul, Livingston, Imrie, Heather, Migot-Nabias, Florence, Brown, Stuart M, McVean, Gilean A. V, Day, Karen P
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828697/