Modification of a Hydrophobic Layer by a Point Mutation in Syntaxin 1A Regulates the Rate of Synaptic Vesicle Fusion
Both constitutive secretion and Ca2+-regulated exocytosis require the assembly of the soluble N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) complexes. At present, little is known about how the SNARE complexes mediating these two distinct pathways differ in structure. Using th...
Main Authors: | , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2007
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808484/ |