Association of warfarin dose with genes involved in its action and metabolism

We report an extensive study of variability in genes encoding proteins that are believed to be involved in the action and biotransformation of warfarin. Warfarin is a commonly prescribed anticoagulant that is difficult to use because of the wide interindividual variation in dose requirements, the na...

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Bibliographic Details
Main Authors: Wadelius, Mia, Chen, Leslie Y., Eriksson, Niclas, Bumpstead, Suzannah, Ghori, Jilur, Wadelius, Claes, Bentley, David, McGinnis, Ralph, Deloukas, Panos
Format: Online
Language:English
Published: Springer-Verlag 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797064/