Pathophysiology of focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease...

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Main Authors: Reidy, Kimberly, Kaskel, Frederick J.
Format: Online
Language:English
Published: Springer-Verlag 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/
id pubmed-1794138
recordtype oai_dc
spelling pubmed-17941382007-02-21 Pathophysiology of focal segmental glomerulosclerosis Reidy, Kimberly Kaskel, Frederick J. Educational Feature Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS. Springer-Verlag 2007-01-10 2007-03 /pmc/articles/PMC1794138/ /pubmed/17216262 http://dx.doi.org/10.1007/s00467-006-0357-2 Text en © IPNA 2007
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Reidy, Kimberly
Kaskel, Frederick J.
spellingShingle Reidy, Kimberly
Kaskel, Frederick J.
Pathophysiology of focal segmental glomerulosclerosis
author_facet Reidy, Kimberly
Kaskel, Frederick J.
author_sort Reidy, Kimberly
title Pathophysiology of focal segmental glomerulosclerosis
title_short Pathophysiology of focal segmental glomerulosclerosis
title_full Pathophysiology of focal segmental glomerulosclerosis
title_fullStr Pathophysiology of focal segmental glomerulosclerosis
title_full_unstemmed Pathophysiology of focal segmental glomerulosclerosis
title_sort pathophysiology of focal segmental glomerulosclerosis
description Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS.
publisher Springer-Verlag
publishDate 2007
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1794138/
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