Pharmacology and Surface Electrostatics of the K Channel Outer Pore Vestibule

In spite of a generally well-conserved outer vestibule and pore structure, there is considerable diversity in the pharmacology of K channels. We have investigated the role of specific outer vestibule charged residues in the pharmacology of K channels using tetraethylammonium (TEA) and a trivalent TE...

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Bibliographic Details
Main Authors: Quinn, Claire C., Begenisich, Ted
Format: Online
Language:English
Published: Springer-Verlag 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1784061/