Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA

Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation.

Bibliographic Details
Main Authors: Deng, Guo-Min, Tarkowski, Andrej
Format: Online
Language:English
Published: BioMed Central 2001
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17824/