Diphenyleneiodonium inhibits NF-kappaB activation and iNOS expression induced by IL-1beta: involvement of reactive oxygen species.
AIMS: In this work, we studied the mechanisms by which diphenyleneiodonium chloride (DPI) inhibits nitric oxide (NO) synthesis induced by the proinflammatory cytokine interleukin-1beta (IL-1) in bovine articular chondrocytes. To achieve this, we evaluated the ability of DPI to inhibit the expression...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2001
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781711/ |