Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy.

BACKGROUND: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes. AIMS: The present stu...

Full description

Bibliographic Details
Main Authors: Dalmarco, Eduardo Monguilhott, Fröde, Tânia Silvia, Medeiros, Yara Santos
Format: Online
Language:English
Published: 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781680/