A Role for the Adult Fat Body in Drosophila Male Courtship Behavior

Mating behavior in Drosophila depends critically on the sexual identity of specific regions in the brain, but several studies have identified courtship genes that express products only outside the nervous system. Although these genes are each active in a variety of non-neuronal cell types, they are...

Full description

Bibliographic Details
Main Authors:	Lazareva, Anna A, Roman, Gregg, Mattox, William, Hardin, Paul E, Dauwalder, Brigitte
Format:	Online
Language:	English
Published:	Public Library of Science 2007
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781494/

id	pubmed-1781494
recordtype	oai_dc
spelling	pubmed-17814942007-01-25 A Role for the Adult Fat Body in Drosophila Male Courtship Behavior Lazareva, Anna A Roman, Gregg Mattox, William Hardin, Paul E Dauwalder, Brigitte Research Article Mating behavior in Drosophila depends critically on the sexual identity of specific regions in the brain, but several studies have identified courtship genes that express products only outside the nervous system. Although these genes are each active in a variety of non-neuronal cell types, they are all prominently expressed in the adult fat body, suggesting an important role for this tissue in behavior. To test its role in male courtship, fat body was feminized using the highly specific Larval serum protein promoter. We report here that the specific feminization of this tissue strongly reduces the competence of males to perform courtship. This effect is limited to the fat body of sexually mature adults as the feminization of larval fat body that normally persists in young adults does not affect mating. We propose that feminization of fat body affects the synthesis of male-specific secreted circulating proteins that influence the central nervous system. In support of this idea, we demonstrate that Takeout, a protein known to influence mating, is present in the hemolymph of adult males but not females and acts as a secreted protein. Public Library of Science 2007-01 2007-01-26 /pmc/articles/PMC1781494/ /pubmed/17257054 http://dx.doi.org/10.1371/journal.pgen.0030016 Text en © 2007 Lazareva et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lazareva, Anna A Roman, Gregg Mattox, William Hardin, Paul E Dauwalder, Brigitte
spellingShingle	Lazareva, Anna A Roman, Gregg Mattox, William Hardin, Paul E Dauwalder, Brigitte A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
author_facet	Lazareva, Anna A Roman, Gregg Mattox, William Hardin, Paul E Dauwalder, Brigitte
author_sort	Lazareva, Anna A
title	A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
title_short	A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
title_full	A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
title_fullStr	A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
title_full_unstemmed	A Role for the Adult Fat Body in Drosophila Male Courtship Behavior
title_sort	role for the adult fat body in drosophila male courtship behavior
description	Mating behavior in Drosophila depends critically on the sexual identity of specific regions in the brain, but several studies have identified courtship genes that express products only outside the nervous system. Although these genes are each active in a variety of non-neuronal cell types, they are all prominently expressed in the adult fat body, suggesting an important role for this tissue in behavior. To test its role in male courtship, fat body was feminized using the highly specific Larval serum protein promoter. We report here that the specific feminization of this tissue strongly reduces the competence of males to perform courtship. This effect is limited to the fat body of sexually mature adults as the feminization of larval fat body that normally persists in young adults does not affect mating. We propose that feminization of fat body affects the synthesis of male-specific secreted circulating proteins that influence the central nervous system. In support of this idea, we demonstrate that Takeout, a protein known to influence mating, is present in the hemolymph of adult males but not females and acts as a secreted protein.
publisher	Public Library of Science
publishDate	2007
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1781494/
_version_	1611393441508360192

A Role for the Adult Fat Body in Drosophila Male Courtship Behavior

Similar Items