Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury

Acute full thickness joint surface defects can undergo repair, which involves tissue patterning and endochondral bone formation. Molecular signals regulating this process may contribute to the repair outcome, chronic evolution and, eventually, the onset of osteoarthritis. We tested the hypothesis th...

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Bibliographic Details
Main Authors: Dell'Accio, Francesco, De Bari, Cosimo, El Tawil, Noha MF, Barone, Francesca, Mitsiadis, Thimios A, O'Dowd, John, Pitzalis, Costantino
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779445/