Using Phylogeny to Improve Genome-Wide Distant Homology Recognition

The gap between the number of known protein sequences and structures continues to widen, particularly as a result of sequencing projects for entire genomes. Recently there have been many attempts to generate structural assignments to all genes on sets of completed genomes using fold-recognition meth...

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Bibliographic Details
Main Authors: Abeln, Sanne, Teubner, Carlo, Deane, Charlotte M
Format: Online
Language:English
Published: Public Library of Science 2007
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779300/