Dissecting Oct3/4-Regulated Gene Networks in Embryonic Stem Cells by Expression Profiling

Dissecting Oct3/4-Regulated Gene Networks in Embryonic Stem Cells by Expression Profiling

POU transcription factor Pou5f1 (Oct3/4) is required to maintain ES cells in an undifferentiated state. Here we show that global expression profiling of Oct3/4-manipulated ES cells delineates the downstream target genes of Oct3/4. Combined with data from genome-wide chromatin-immunoprecipitation (Ch...

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Bibliographic Details
Main Authors: Matoba, Ryo, Niwa, Hitoshi, Masui, Shinji, Ohtsuka, Satoshi, Carter, Mark G., Sharov, Alexei A., Ko, Minoru S.H.
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762406/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762406/

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