Requirement of TORC1 for Late-Phase Long-Term Potentiation in the Hippocampus
Late-phase long-term potentiation (L-LTP) and long-term memory depend on the transcription of mRNA of CRE-driven genes and synthesis of proteins. However, how synaptic signals propagate to the nucleus is unclear. Here we report that the CREB coactivator TORC1 (transducer of regulated CREB activity 1...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762377/ |