Requirement of TORC1 for Late-Phase Long-Term Potentiation in the Hippocampus

Late-phase long-term potentiation (L-LTP) and long-term memory depend on the transcription of mRNA of CRE-driven genes and synthesis of proteins. However, how synaptic signals propagate to the nucleus is unclear. Here we report that the CREB coactivator TORC1 (transducer of regulated CREB activity 1...

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Bibliographic Details
Main Authors: Zhou, Yang, Wu, Hao, Li, Shuai, Chen, Qian, Cheng, Xue-Wen, Zheng, Jing, Takemori, Hiroshi, Xiong, Zhi-Qi
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762377/