Genetic Analysis of the Roles of BMP2, BMP4, and BMP7 in Limb Patterning and Skeletogenesis

Bone morphogenetic protein (BMP) family members, including BMP2, BMP4, and BMP7, are expressed throughout limb development. BMPs have been implicated in early limb patterning as well as in the process of skeletogenesis. However, due to complications associated with early embryonic lethality, particu...

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Bibliographic Details
Main Authors: Bandyopadhyay, Amitabha, Tsuji, Kunikazu, Cox, Karen, Harfe, Brian D, Rosen, Vicki, Tabin, Clifford J
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1713256/