Apolipoprotein E decreases tau kinases and phospho-tau levels in primary neurons
Apolipoprotein E (apoE) receptors act as signaling molecules in neurons, altering phosphorylation of numerous proteins after extracellular ligand binding and affecting neurite outgrowth, synapse formation, and neuronal migration. Since apoE is important in the pathogenesis of Alzheimer's diseas...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1713232/ |