DNA Microarrays in Herbal Drug Research

Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional s...

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Main Authors:	Chavan, Preeti, Joshi, Kalpana, Patwardhan, Bhushan
Format:	Online
Language:	English
Published:	Oxford University Press 2006
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1697755/

id	pubmed-1697755
recordtype	oai_dc
spelling	pubmed-16977552006-12-14 DNA Microarrays in Herbal Drug Research Chavan, Preeti Joshi, Kalpana Patwardhan, Bhushan Review Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional strategies for expression profiling are optimized for single gene analysis. DNA microarrays serve as suitable high throughput tool for simultaneous analysis of multiple genes. Major practical applicability of DNA microarrays remains in DNA mutation and polymorphism analysis. This review highlights applications of DNA microarrays in pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts. Oxford University Press 2006-12 2006-10-27 /pmc/articles/PMC1697755/ /pubmed/17173108 http://dx.doi.org/10.1093/ecam/nel075 Text en © 2006 The Author(s)
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Chavan, Preeti Joshi, Kalpana Patwardhan, Bhushan
spellingShingle	Chavan, Preeti Joshi, Kalpana Patwardhan, Bhushan DNA Microarrays in Herbal Drug Research
author_facet	Chavan, Preeti Joshi, Kalpana Patwardhan, Bhushan
author_sort	Chavan, Preeti
title	DNA Microarrays in Herbal Drug Research
title_short	DNA Microarrays in Herbal Drug Research
title_full	DNA Microarrays in Herbal Drug Research
title_fullStr	DNA Microarrays in Herbal Drug Research
title_full_unstemmed	DNA Microarrays in Herbal Drug Research
title_sort	dna microarrays in herbal drug research
description	Natural products are gaining increased applications in drug discovery and development. Being chemically diverse they are able to modulate several targets simultaneously in a complex system. Analysis of gene expression becomes necessary for better understanding of molecular mechanisms. Conventional strategies for expression profiling are optimized for single gene analysis. DNA microarrays serve as suitable high throughput tool for simultaneous analysis of multiple genes. Major practical applicability of DNA microarrays remains in DNA mutation and polymorphism analysis. This review highlights applications of DNA microarrays in pharmacodynamics, pharmacogenomics, toxicogenomics and quality control of herbal drugs and extracts.
publisher	Oxford University Press
publishDate	2006
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1697755/
_version_	1611391933633003520

DNA Microarrays in Herbal Drug Research

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