Both introns and long 3′-UTRs operate as cis-acting elements to trigger nonsense-mediated decay in plants

Both introns and long 3′-UTRs operate as cis-acting elements to trigger nonsense-mediated decay in plants

Nonsense-mediated mRNA decay (NMD) is a eukaryotic quality control mechanism that identifies and eliminates aberrant mRNAs containing a premature termination codon (PTC). Although, key trans-acting NMD factors, UPF1, UPF2 and UPF3 are conserved in yeast and mammals, the cis-acting NMD elements are d...

Full description

Bibliographic Details
Main Authors: Kertész, Sándor, Kerényi, Zoltán, Mérai, Zsuzsanna, Bartos, Imre, Pálfy, Tamás, Barta, Endre, Silhavy, Dániel
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693880/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693880/

Similar Items