Multiple alignment of protein sequences with repeats and rearrangements

Multiple sequence alignments are the usual starting point for analyses of protein structure and evolution. For proteins with repeated, shuffled and missing domains, however, traditional multiple sequence alignment algorithms fail to provide an accurate view of homology between related proteins, beca...

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Bibliographic Details
Main Authors: Phuong, Tu Minh, Do, Chuong B., Edgar, Robert C., Batzoglou, Serafim
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635250/