Two-Stage Two-Locus Models in Genome-Wide Association

Studies in model organisms suggest that epistasis may play an important role in the etiology of complex diseases and traits in humans. With the era of large-scale genome-wide association studies fast approaching, it is important to quantify whether it will be possible to detect interacting loci usin...

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Bibliographic Details
Main Authors: Evans, David M, Marchini, Jonathan, Morris, Andrew P, Cardon, Lon R
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570380/