Tumor promoters and cocarcinogens in tobacco carcinogenesis.

Cigarette smoke induces carcinoma of the larynx in Syrian golden hamsters and is active as a tumor promoter in hamsters pretreated with a low dose of a PAH, nitrosamine, or nitrosamide. These tumorigenic effects are only observed with total smoke, but not with the gas phase alone. This demonstrates...

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Bibliographic Details
Main Authors: Hoffmann, D, Hecht, S S, Wynder, E L
Format: Online
Language:English
Published: 1983
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569210/