Effect of metals on mutagenesis and DNA repair.
Unlike the situation with organic compounds, metals do not show a high correlation between carcinogenicity and mutagenicity. An agent may be mutagenic by causing misreplication of DNA due to alterations of the DNA template, decreased fidelity of DNA polymerase, or inhibition of the proofreading of D...
| Main Author: | |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
1981
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568811/ |