Role of radical cations in aromatic hydrocarbon carcinogenesis.
Carcinogenic activation of polycyclic aromatic hydrocarbons (PAH) involves two main pathways: one-electron oxidation and monooxygenation. One-electron oxidation produces PAH radical cations, which can react with cellular nucleophiles. Results from biochemical and biological experiments indicate that...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
1985
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568595/ |