Molecular and functional analysis of tumor-suppressor genes by transfection.

The transformed and tumorigenic phenotype of H-ras transfected rat FE-8 cells can be suppressed by cell fusion with normal rat embryo fibroblasts. Transfection into FE-8 cells of DNA prepared from normal human placenta followed by selective elimination of tumorigenic transfected cell clones resulted...

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Bibliographic Details
Main Authors: Schäfer, R, Iyer, J, Iten, E, Nirkko, A C, Balmer, J, Klemenz, R
Format: Online
Language:English
Published: 1991
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568050/