Activation of cellular oncogenes by chemical carcinogens in Syrian hamster embryo fibroblasts.
Carcinogen-induced point mutations resulting in activation of ras oncogenes have been demonstrated in various experimental systems such as skin carcinogenesis, mammary, and liver carcinogenesis. In many cases, the data support the conclusion that these point mutations are critical changes in the ini...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1990
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568019/ |