Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989

Cadmium is a cumulative environmental pollutant. For the general population mainly exposed by the oral route and through tobacco smoke inhalation, the kidney is the critical organ. Belgium is the principal producer of cadmium in Europe, and certain areas of the country are polluted by cadmium mainly...

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Main Authors:	Lauwerys, Robert, Amery, Antoon, Bernard, Alfred, Bruaux, Pierre, Buchet, Jean-Pierre, Claeys, Françoise, De Plaen, Pierre, Ducoffre, Geneviève, Fagard, Robert, Lijnen, Paul, Nick, Laurence, Roels, Harry, Rondia, Désiré, Saint-Remy, Annie, Sartor, Francis, Staessen, Jan
Format:	Online
Language:	English
Published:	1990
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567839/

id	pubmed-1567839
recordtype	oai_dc
spelling	pubmed-15678392006-09-18 Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989 Lauwerys, Robert Amery, Antoon Bernard, Alfred Bruaux, Pierre Buchet, Jean-Pierre Claeys, Françoise De Plaen, Pierre Ducoffre, Geneviève Fagard, Robert Lijnen, Paul Nick, Laurence Roels, Harry Rondia, Désiré Saint-Remy, Annie Sartor, Francis Staessen, Jan Contributed Articles Cadmium is a cumulative environmental pollutant. For the general population mainly exposed by the oral route and through tobacco smoke inhalation, the kidney is the critical organ. Belgium is the principal producer of cadmium in Europe, and certain areas of the country are polluted by cadmium mainly because of past emissions from nonferrous industries. Preliminary studies carried out in one polluted area have suggested that environmental pollution might lead to an increased uptake of cadmium by the human body and possibly to health effects. Thus, a large-scale morbidity study has been initiated to assess the validity of this hypothesis. The present paper describes the protocol of this study. Its main objectives are to determine to what extent environmental exposure to cadmium resulting from industrial emissions may lead to accumulation of the metal in the human organism; to establish whether or not environmental exposure may induce renal changes and/or influence blood pressure; and to assess the acceptable internal dose of cadmium for the general population. The study design takes advantage of the fact that biological indicators of exposure, body burden, and early nephrotoxic effects of cadmium are available, which increase the likelihood of detecting a cause-effect relationship. 1990-07 /pmc/articles/PMC1567839/ /pubmed/2269233 Text en
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Lauwerys, Robert Amery, Antoon Bernard, Alfred Bruaux, Pierre Buchet, Jean-Pierre Claeys, Françoise De Plaen, Pierre Ducoffre, Geneviève Fagard, Robert Lijnen, Paul Nick, Laurence Roels, Harry Rondia, Désiré Saint-Remy, Annie Sartor, Francis Staessen, Jan
spellingShingle	Lauwerys, Robert Amery, Antoon Bernard, Alfred Bruaux, Pierre Buchet, Jean-Pierre Claeys, Françoise De Plaen, Pierre Ducoffre, Geneviève Fagard, Robert Lijnen, Paul Nick, Laurence Roels, Harry Rondia, Désiré Saint-Remy, Annie Sartor, Francis Staessen, Jan Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
author_facet	Lauwerys, Robert Amery, Antoon Bernard, Alfred Bruaux, Pierre Buchet, Jean-Pierre Claeys, Françoise De Plaen, Pierre Ducoffre, Geneviève Fagard, Robert Lijnen, Paul Nick, Laurence Roels, Harry Rondia, Désiré Saint-Remy, Annie Sartor, Francis Staessen, Jan
author_sort	Lauwerys, Robert
title	Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
title_short	Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
title_full	Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
title_fullStr	Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
title_full_unstemmed	Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989
title_sort	health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in belgium from 1985 to 1989
description	Cadmium is a cumulative environmental pollutant. For the general population mainly exposed by the oral route and through tobacco smoke inhalation, the kidney is the critical organ. Belgium is the principal producer of cadmium in Europe, and certain areas of the country are polluted by cadmium mainly because of past emissions from nonferrous industries. Preliminary studies carried out in one polluted area have suggested that environmental pollution might lead to an increased uptake of cadmium by the human body and possibly to health effects. Thus, a large-scale morbidity study has been initiated to assess the validity of this hypothesis. The present paper describes the protocol of this study. Its main objectives are to determine to what extent environmental exposure to cadmium resulting from industrial emissions may lead to accumulation of the metal in the human organism; to establish whether or not environmental exposure may induce renal changes and/or influence blood pressure; and to assess the acceptable internal dose of cadmium for the general population. The study design takes advantage of the fact that biological indicators of exposure, body burden, and early nephrotoxic effects of cadmium are available, which increase the likelihood of detecting a cause-effect relationship.
publishDate	1990
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567839/
_version_	1611388387060613120

Health effects of environmental exposure to cadmium: objectives, design and organization of the cadmibel study: a cross-sectional morbidity study carried out in Belgium from 1985 to 1989

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