Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.
1,3-Butadiene, a large-production volume chemical used mainly in the manufacture of synthetic rubber, was found to induce multiple-organ carcinogenicity in male and female B6C3F1 mice at exposure concentrations (625 and 1250 ppm) equivalent to and below the OSHA standard of 1000 ppm. Since this stud...
Main Authors: | , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
1990
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567751/ |