The role of humic substances in drinking water in Kashin-Beck disease in China.

We conducted in vitro and in vivo assays in a selenium-deficient system to determine if organic matter (mainly fulvic acid; FA) is involved in a free radical mechanism of action for Kashin-Beck disease. Cartilage cell culture experiments indicated that the oxy or hydroxy functional groups in FA may...

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Bibliographic Details
Main Authors: Peng, A, Wang, W H, Wang, C X, Wang, Z J, Rui, H F, Wang, W Z, Yang, Z W
Format: Online
Language:English
Published: 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566521/