Heme Deficiency in Alzheimer's Disease: A Possible Connection to Porphyria

Mechanisms that cause Alzheimer's disease (AD), an invariably fatal neurodegenerative disease, are unknown. Important recent data indicate that neuronal heme deficiency may contribute to AD pathogenesis. If true, factors that contribute to the intracellular heme deficiency could potentially alt...

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Bibliographic Details
Main Authors: Dwyer, Barney E., Stone, Meghan L., Zhu, Xiongwei, Perry, George, Smith, Mark A.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559910/