Uncoiling Mechanics of Escherichia coli Type I Fimbriae Are Optimized for Catch Bonds

We determined whether the molecular structures through which force is applied to receptor–ligand pairs are tuned to optimize cell adhesion under flow. The adhesive tethers of our model system, Escherichia coli, are type I fimbriae, which are anchored to the outer membrane of most E. coli strains. Th...

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Bibliographic Details
Main Authors: Forero, Manu, Yakovenko, Olga, Sokurenko, Evgeni V, Thomas, Wendy E, Vogel, Viola
Format: Online
Language:English
Published: Public Library of Science 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557399/