Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120

During natural HIV infection, an array of host receptors are thought to influence virus attachment and the kinetics of infection. In this study, to probe the interactions of HIV envelope (Env) with various receptors, we assessed the inhibitory properties of various anti-Env monoclonal antibodies (mA...

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Bibliographic Details
Main Authors: Binley, James M, Ngo-Abdalla, Stacie, Moore, Penny, Bobardt, Michael, Chatterji, Udayan, Gallay, Philippe, Burton, Dennis R, Wilson, Ian A, Elder, John H, de Parseval, Aymeric
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543650/