Complex roles for telomeres and telomerase in breast carcinogenesis
Telomerase – an enzyme that endows cells with unlimited proliferative potential – is differentially expressed in cancer cells and in normal cells. Although most primary human cells lack telomerase, the enzyme is upregulated in more than 90% of invasive breast cancers. As a result, much of breast can...
Main Author: | |
---|---|
Format: | Online |
Language: | English |
Published: |
BioMed Central
2003
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154132/ |