HHsenser: exhaustive transitive profile search using HMM–HMM comparison

HHsenser is the first server to offer exhaustive intermediate profile searches, which it combines with pairwise comparison of hidden Markov models. Starting from a single protein sequence or a multiple alignment, it can iteratively explore whole superfamilies, producing few or no false positives. Th...

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Bibliographic Details
Main Authors: Söding, Johannes, Remmert, Michael, Biegert, Andreas, Lupas, Andrei N.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538784/