Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

To examine whether the lack of sufficient neoangiogenesis in systemic sclerosis (SSc) is caused by a decrease in angiogenic factors and/or an increase in angiostatic factors, the potent proangiogenic molecules vascular endothelial growth factor (VEGF) and basic fibroblast growth factor, and the angi...

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Bibliographic Details
Main Authors: Distler, Oliver, del Rosso, Angela, Giacomelli, Roberto, Cipriani, Paola, Conforti, Maria L, Guiducci, Serena, Gay, Renate E, Michel, Beat A, Brühlmann, Pius, Müller-Ladner, Ulf, Gay, Steffen, Matucci-Cerinic, Marco
Format: Online
Language:English
Published: BioMed Central 2002
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153841/