52-kDa Ro/SSA epitopes preferentially recognized by antibodies from mothers of children with neonatal lupus and congenital heart block

Neonatal lupus erythematosus is a rare disorder caused by the transplacental passage of maternal autoantibodies. The 52-kDa Ro/SSA antigen (Ro52) ribonucleoprotein represents an antigenic target strongly associated with the autoimmune response in mothers whose children have neonatal lupus and cardia...

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Bibliographic Details
Main Authors: Fritsch, Christine, Hoebeke, Johan, Dali, Hayet, Ricchiuti, Vincent, Isenberg, David A, Meyer, Olivier, Muller, Sylviane
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1526571/