Phagolysosomal pH and dissolution of cobalt oxide particles by alveolar macrophages.
We studied phagolysosomal pH in rabbit alveolar macrophages (AM) incubated with 0-15 microM chloroquine. There was a dose-related increase in pH with chloroquine concentration. Electron microscopy showed that chloroquine increased lysosomal size. In a second experiment we studied dissolution of radi...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519542/ |