Cell proliferation and renal carcinogenesis.
Enhanced cell proliferation occurs at several stages of renal tumorigenesis. Initiation by genotoxic nephrocarcinogens such as dimethylnitrosamine (DMN) is likely a result of DNA damage coupled with an initial burst of DNA synthesis associated with the cytotoxic effects of the compound. The level of...
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| Format: | Online |
| Language: | English |
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1993
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519426/ |