Pathological and physiological functions of presenilins

Mutations in PSEN1 and PSEN2 genes account for the majority of cases of early-onset familial Alzheimer disease. Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both academia and pharmaceutical industry have sought to unrav...

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Bibliographic Details
Main Authors: Vetrivel, Kulandaivelu S, Zhang, Yun-wu, Xu, Huaxi, Thinakaran, Gopal
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513131/