Pathological and physiological functions of presenilins
Mutations in PSEN1 and PSEN2 genes account for the majority of cases of early-onset familial Alzheimer disease. Since the first prediction of a genetic link between PSEN1 and PSEN2 with Alzheimer's disease, many research groups from both academia and pharmaceutical industry have sought to unrav...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2006
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513131/ |