Mevalonate kinase deficiencies: from mevalonic aciduria to hyperimmunoglobulinemia D syndrome
Mevalonic aciduria (MVA) and hyperimmunoglobulinemia D syndrome (HIDS) represent the two ends of a clinical spectrum of disease caused by deficiency of mevalonate kinase (MVK), the first committed enzyme of cholesterol biosynthesis. At least 30 patients with MVA and 180 patients with HIDS have been...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2006
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475558/ |