The toxicity of inhaled methyl isocyanate in F344/N rats and B6C3F1 mice. II. Repeated exposure and recovery studies.

F344/N rats and B6C3F1 mice were exposed to 0, 1, 3, or 6 ppm methyl isocyanate by inhalation for 6 hr on 4 consecutive days. Deaths of rats were observed following 3 ppm exposures, and mice died after exposures to 6 ppm. Deaths appeared to be related to severe respiratory distress. Survivors in hig...

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Bibliographic Details
Main Authors: Bucher, J R, Gupta, B N, Thompson, M, Adkins, B, Schwetz, B A
Format: Online
Language:English
Published: 1987
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474630/