Mutations and homologous recombination induced in mammalian cells by metabolites of benzo[a]pyrene and 1-nitropyrene.
Metabolites of two structurally related chemical carcinogens, benzo[a]pyrene and 1-nitropyrene, were compared for their ability to cause cytotoxicity and induce mutations in normally repairing or nucleotide excision repair-deficient diploid human fibroblasts; for their ability to induce mutations in...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
1987
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474479/ |