Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element

Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element

Genomes and antigenomes of many positive-strand RNA viruses contain 3′-poly(A) and 5′-poly(U) tracts, respectively, serving as mutual templates. Mechanism(s) controlling the length of these homopolymeric stretches are not well understood. Here, we show that in coxsackievirus B3 (CVB3) and three othe...

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Bibliographic Details
Main Authors: van Ooij, Mark J. M., Polacek, Charlotta, Glaudemans, Dirk H. R. F., Kuijpers, Judith, van Kuppeveld, Frank J. M., Andino, Raul, Agol, Vadim I., Melchers, Willem J. G.
Format: Online
Language:English
Published: Oxford University Press 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474053/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474053/

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